Summary & Key Points
"EBO-PEP is a consortium of partners aiming to expand the portfolio of therapeutic tools against MVE by evaluating a PPE strategy for high-risk contacts and maintaining a network for knowledge sharing and collaboration around PPE."
EBO-PEP is a consortium of partners whose goal is to expand the portfolio of therapeutic tools against EVD by evaluating a PEP strategy for high-risk contacts and maintaining a knowledge-sharing and collaboration network around PEP.
In executing the project, experts will conduct a clinical trial in Africa to test the efficacy of treatments used as PEP for high-risk contacts; strengthen the capacity of clinical researchers and increase community knowledge of Ebola virus research; and define the best PEP strategy for high-risk contacts and advocate for PEP implementation in Ebola virus disease-affected countries.
For this collaborative workshop held at the Hôtel Assoyam in Grand-Bassam from September 10 to 13, 2024, partners from France (INSERM (iPLesp, ANRS-MIE), University of Bordeaux, ALIMA, PANTHER), the DRC (INRB), Spain (ISGLOBAL), Belgium (Doctors Without Borders), Senegal (Cheikh Anta Diop University), Côte d’Ivoire (PAC-CI Program), and Guinea (ANSS, CERFIG) met to pre-finalize the protocol and discuss the implementation of the EBO-PEP study.
Several presentations were given, followed by discussions on the clinical trial protocol and the activities of the various working groups. These working groups focus on overall project coordination, scientific coordination, project preparation, clinical trial management, health economics, community engagement, and study acceptability among target populations.
Additionally, participants discussed key elements for project success, including governance of the EBO-PEP consortium, governance of the EBO-PEP project, and the timeline to facilitate implementation.
The next meetings are scheduled for September and December 2024 to finalize the protocol, establish the scientific advisory board and independent monitoring committee, and submit the project.
Participants left very satisfied with the outcomes, the workshop atmosphere, and, for some, the opportunity to discover Grand-Bassam, one of Côte d’Ivoire’s tourist treasures.